Cannabis been a controversial topic among the world for many years, but recently a break through within cannabis has arrived. Cannabinoids are terpenophenolic from the cannabis plant, more specifically Cannabis Sativa. Overall, Cannabis can produce over 113 different cannabinoids all together. Cannabinoids are known for contributing a psychoactive property, which many people are not always wanting when wanting to use this plant to manage illness or discomfort. CBDs on the other hand do not produce a psychoactive property. Cannabinoids have been noted through research how they play a key role in improving the daily lives of individuals when consuming cannabis for medicinal purposes. In order for us to know how they help us function, we need to understand the endocannabinoid system in our bodies.
THC generally activates this system, in such a way that it locks it into the piece almost like a puzzle piece. When individuals are seeking the benefits of CBD, it is typically better for them to ensure that the cannabis products they are consuming contain both CBD and THC. The two work hand in hand, inhibiting each others compounds, increasing the benefits of the cannabis for the person that is consuming. The two types of receptors available are CB1 and CB2. CB1 receptors can primarily be found in our central nervous system, unlocking the psychoactive property in cannabis. CB2 receptors on the other hand are found in the peripheral nervous system reaching out to our muscles, nerve endings, and motor neurons, which can explain why it can help with certain problems like inflammation, pain, digestive aid, anxiety and sleep.
The endocannabinoid system is believed to be a regulator of the digestive system. In turn, this can aid in not only increasing or suppressing appetite (depending on the strain) but also aids in the digestive process. More so, for individuals suffer from disease or illness, or just find it difficult to gain weight, a simpler way to avoid health risk from underweight complication could be to add CBD into ones daily routine.
Mood and memory recalling to emotional or stressful events are linked-to many cases of anxiety. These are believed to be linked to the endocannabinoid system and although small, can be very impactful. The correlation is relative to how individuals may feel. The sense of belonging is a common human emotional validation and when people feel as though we do, our overall well-being and often even mood can be enhanced. CBDs can help bridge the gap between our emotional state by enhancing the state of emotion we are in.
The feeling of physical pain is a predominant complaint of many individuals all over the world. Pain is subjective in all aspects, but the quality of life is far too precious to be taken for granted. Certain cannabinoids are responsible for being analgesics and can effect symptoms like pain or discomfort through CB1 and CB2 receptors via supra and paraspinal pathways, both ascending and descending. Similar to opioids, cannabis can be used to mitigate pain through these pathways within the body.
Baker, D., Pryce G., Giovanni, G. et al.: The Therapeutic Potential of Cannabis. Lancet Neurol 2 (5): 291- 8, 2003.
Khasabova, IA. Gielissen, J., Chandiramani, A., et al.: CB1 and CB2 Receptor Agonists Promote Analgesia Through Synergy in a Murine Model of Tumor Pain. Behav Pharmacy 22 (5-6): 607- 16, 2011.
Richardson, JD., Kilo, S., Hargreaves, KM.: Cannabinoids Reduce Hyperalgesia and Inflammation via Interaction With Peripheral CB1 Receptors. Pain 75 (1): 111-9, 1998.
Walker, JM., Hohmann, AG., Martin, WJ. et al.: The Neurobiology of Cannabinoid Analgesia. Life Sci 65 (6-7): 665-73, 1999.